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923-FG7 伯楨生物(bioGenous) Recombinant Human FGF7

欄目：生長(zhǎng)因子及小分子（用于類(lèi)器官培養(yǎng)）
923-FG7 伯楨生物(bioGenous) Recombinant Human FGF7
貨號(hào)：923-FG7-1mg；
923-FG7-100μg；
品牌： 伯楨生物(bioGenous)

產(chǎn)品介紹


產(chǎn)品編號(hào)

產(chǎn)品名稱(chēng)

    包裝規(guī)格    

     價(jià)格    

      923-FG7-1mg       

     Recombinant Human FGF7     

1mg

10494

  923-FG7-100μg 

Recombinant Human FGF7

100μg

1799


DESCRIPTION

Background:

FGF-7 (fibroblast growth factor-7) is one of 22 known members of the mouse FGF family of secreted proteins that plays a key role in development, morphogenesis, angiogenesis, wound healing, and tumorigenesis[1].FGF-7 promotes cell migration and invasion, and mediates melanocyte transfer to keratinocytes upon UVB radiation[2]. It has been used ectopically to avoid chemotherapy-induced oral mucositis in patients with hematological malignancies. Deletion of FGF-7 affects kidney development, producing abnormally small ureteric buds and fewer nephrons[3] . It also impedes hair follicle differentiation [4]. The 194 amino acid (aa) FGF-7 precursor contains a 31 aa signal sequence and, like all other FGFs, an ~120 aa beta -trefoil scaffold that includes receptor- and heparin-binding sites.

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